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APOBEC3G and APOBEC3F rarely co-mutate the same HIV genome

BACKGROUND: The human immune proteins APOBEC3G and APOBEC3F (hA3G and hA3F) induce destructive G-to-A changes in the HIV genome, referred to as ‘hypermutation’. These two proteins co-express in human cells, co-localize to mRNA processing bodies and might co-package into HIV virions. Therefore they a...

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Detalles Bibliográficos
Autores principales:	Ebrahimi, Diako, Anwar, Firoz, Davenport, Miles P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532371/ https://www.ncbi.nlm.nih.gov/pubmed/23256516 http://dx.doi.org/10.1186/1742-4690-9-113

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