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Upregulation of Cystathionine β-Synthetase Expression Contributes to Visceral Hyperalgesia Induced by Heterotypic Intermittent Stress in Rats

BACKGROUND: Hydrogen sulfide (H(2)S) functions as a neuromodulator, but whether it modulates visceral pain is not well known. This study was designed to determine the role for the endogenous H(2)S producing enzyme cystathionine β-synthetase (CBS) and cystathionine γ-lyase (CSE) in a validated rat mo...

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Detalles Bibliográficos
Autores principales: Wang, Yongmeng, Qu, Ruobing, Hu, Shufen, Xiao, Ying, Jiang, Xinghong, Xu, Guang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532424/
https://www.ncbi.nlm.nih.gov/pubmed/23285261
http://dx.doi.org/10.1371/journal.pone.0053165