Diverged Alleles of the Anopheles gambiae Leucine-Rich Repeat Gene APL1A Display Distinct Protective Profiles against Plasmodium falciparum

Functional studies have demonstrated a role for the Anopheles gambiae APL1A gene in resistance against the human malaria parasite, Plasmodium falciparum. Here, we exhaustively characterize the structure of the APL1 locus and show that three structurally different APL1A alleles segregate in the Ngous...

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Detalles Bibliográficos
Autores principales: Holm, Inge, Lavazec, Catherine, Garnier, Thierry, Mitri, Christian, Riehle, Michelle M., Bischoff, Emmanuel, Brito-Fravallo, Emma, Takashima, Eizo, Thiery, Isabelle, Zettor, Agnes, Petres, Stephane, Bourgouin, Catherine, Vernick, Kenneth D., Eiglmeier, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532451/
https://www.ncbi.nlm.nih.gov/pubmed/23285147
http://dx.doi.org/10.1371/journal.pone.0052684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532451/
https://www.ncbi.nlm.nih.gov/pubmed/23285147
http://dx.doi.org/10.1371/journal.pone.0052684

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