Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

Multidomain proteins incorporating interaction domains are central to regulation of cellular processes. The elucidation of structural organization and mechanistic insights into many of these proteins, however, remain challenging due to their inherent flexibility. Here, we describe the organization a...

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Detalles Bibliográficos
Autores principales: Bunney, Tom D., Esposito, Diego, Mas-Droux, Corine, Lamber, Ekatarina, Baxendale, Rhona W., Martins, Marta, Cole, Ambrose, Svergun, Dmitri, Driscoll, Paul C., Katan, Matilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532599/
https://www.ncbi.nlm.nih.gov/pubmed/23063561
http://dx.doi.org/10.1016/j.str.2012.09.005

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