Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis

SUMMARY: Background: In comparison to the classical isoforms of protein kinase C (PKC), the novel isoforms are thought to play minor or inhibitory roles in the regulation of platelet activation and thrombosis. OBJECTIVES: To measure the levels of PKCθ and PKCε and to investigate the phenotype of mic...

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Detalles Bibliográficos
Autores principales: UNSWORTH, A J, FINNEY, B A, NAVARRO-NUNEZ, L, SEVERIN, S, WATSON, S P, PEARS, C J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Platelets
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532618/
https://www.ncbi.nlm.nih.gov/pubmed/22812584
http://dx.doi.org/10.1111/j.1538-7836.2012.04857.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532618/
https://www.ncbi.nlm.nih.gov/pubmed/22812584
http://dx.doi.org/10.1111/j.1538-7836.2012.04857.x

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