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Kainic Acid-Induced Seizures Modulate Akt (SER473) Phosphorylation in the Hippocampus of Dopamine D2 Receptor Knockout Mice

Dopamine D2 receptor (D2R) signalling has been shown to modulate seizure-induced hippocampal cell death. D2R knockout (D2R−/−) mice are more susceptible to kainic acid (KA)-induced excitotoxicity, displaying cell death in the CA3 subfield of the hippocampus at KA doses not damaging in wild-type (WT)...

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Detalles Bibliográficos
Autores principales:	Dunleavy, Mark, Provenzano, Giovanni, Henshall, David C., Bozzi, Yuri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Humana Press Inc 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532719/ https://www.ncbi.nlm.nih.gov/pubmed/23188702 http://dx.doi.org/10.1007/s12031-012-9927-x

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