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Extensive structural change of the envelope protein of dengue virus induced by a tuned ionic strength: conformational and energetic analyses

The Dengue has become a global public health threat, with over 100 million infections annually; to date there is no specific vaccine or any antiviral drug. The structures of the envelope (E) proteins of the four known serotype of the dengue virus (DENV) are already known, but there are insufficient...

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Detalles Bibliográficos
Autores principales: Degrève, Léo, Fuzo, Carlos A., Caliri, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532723/
https://www.ncbi.nlm.nih.gov/pubmed/23160852
http://dx.doi.org/10.1007/s10822-012-9616-4