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Extensive structural change of the envelope protein of dengue virus induced by a tuned ionic strength: conformational and energetic analyses
The Dengue has become a global public health threat, with over 100 million infections annually; to date there is no specific vaccine or any antiviral drug. The structures of the envelope (E) proteins of the four known serotype of the dengue virus (DENV) are already known, but there are insufficient...
Autores principales: | Degrève, Léo, Fuzo, Carlos A., Caliri, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532723/ https://www.ncbi.nlm.nih.gov/pubmed/23160852 http://dx.doi.org/10.1007/s10822-012-9616-4 |
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