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Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study

CONTEXT: Antisepsis achieved through appropriate use of irrigants is essential for endodontic success. Identification of newer anti-bacterial agents gives alternatives to clean the canal as eradication of the infection prior to obturation does affect prognosis. OBJECTIVE: Comparison of the anti-bact...

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Autores principales: Mathew, Vinod B., Madhusudhana, Koppolu, Sivakumar, Nuvulla, Venugopal, Thangala, Reddy, Redderu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532785/
https://www.ncbi.nlm.nih.gov/pubmed/23293478
http://dx.doi.org/10.4103/0976-237X.103615
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author Mathew, Vinod B.
Madhusudhana, Koppolu
Sivakumar, Nuvulla
Venugopal, Thangala
Reddy, Redderu K.
author_facet Mathew, Vinod B.
Madhusudhana, Koppolu
Sivakumar, Nuvulla
Venugopal, Thangala
Reddy, Redderu K.
author_sort Mathew, Vinod B.
collection PubMed
description CONTEXT: Antisepsis achieved through appropriate use of irrigants is essential for endodontic success. Identification of newer anti-bacterial agents gives alternatives to clean the canal as eradication of the infection prior to obturation does affect prognosis. OBJECTIVE: Comparison of the anti-bacterial action of 3.8% silver diamine fluoride and 2% chlorhexidine gluconate against Enterococcus faecalis in root canals. MATERIALS AND METHODS: Forty-four single-rooted teeth were decoronated, and the root section was enlarged with peeso-reamer (No: 3) to standardize length and diameter. The samples were then autoclaved and divided into two study groups and two control groups. Enterococcus faecalis ATCC 29212 was inoculated into all test samples for 72 hours. The samples were enlarged with peeso-reamer (No: 5) after placement of respective medicament for 24 hours. Shavings were collected and inoculated on Brain Heart Infusion agar for 24 hrs to measure the colony forming units. RESULTS: Both 3.8% silver diamine fluoride and 2% chlorhexidine showed a superior capacity to sterilize the root canals than control groups. CONCLUSION: The use of silver diamine fluoride as an endodontic irrigant is feasible as it can effectively remove the microbes present in the canal and circumpulpal dentin.
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spelling pubmed-35327852013-01-04 Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study Mathew, Vinod B. Madhusudhana, Koppolu Sivakumar, Nuvulla Venugopal, Thangala Reddy, Redderu K. Contemp Clin Dent Original Article CONTEXT: Antisepsis achieved through appropriate use of irrigants is essential for endodontic success. Identification of newer anti-bacterial agents gives alternatives to clean the canal as eradication of the infection prior to obturation does affect prognosis. OBJECTIVE: Comparison of the anti-bacterial action of 3.8% silver diamine fluoride and 2% chlorhexidine gluconate against Enterococcus faecalis in root canals. MATERIALS AND METHODS: Forty-four single-rooted teeth were decoronated, and the root section was enlarged with peeso-reamer (No: 3) to standardize length and diameter. The samples were then autoclaved and divided into two study groups and two control groups. Enterococcus faecalis ATCC 29212 was inoculated into all test samples for 72 hours. The samples were enlarged with peeso-reamer (No: 5) after placement of respective medicament for 24 hours. Shavings were collected and inoculated on Brain Heart Infusion agar for 24 hrs to measure the colony forming units. RESULTS: Both 3.8% silver diamine fluoride and 2% chlorhexidine showed a superior capacity to sterilize the root canals than control groups. CONCLUSION: The use of silver diamine fluoride as an endodontic irrigant is feasible as it can effectively remove the microbes present in the canal and circumpulpal dentin. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3532785/ /pubmed/23293478 http://dx.doi.org/10.4103/0976-237X.103615 Text en Copyright: © Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mathew, Vinod B.
Madhusudhana, Koppolu
Sivakumar, Nuvulla
Venugopal, Thangala
Reddy, Redderu K.
Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study
title Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study
title_full Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study
title_fullStr Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study
title_full_unstemmed Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study
title_short Anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – An ex vivo study
title_sort anti-microbial efficiency of silver diamine fluoride as an endodontic medicament – an ex vivo study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532785/
https://www.ncbi.nlm.nih.gov/pubmed/23293478
http://dx.doi.org/10.4103/0976-237X.103615
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