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Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series

Background. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy of PDL therapy for mostly facial BCCs. Materials and Method...

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Autores principales: Minars, Norman, Blyumin-Karasik, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532878/
https://www.ncbi.nlm.nih.gov/pubmed/23316366
http://dx.doi.org/10.1155/2012/286480
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author Minars, Norman
Blyumin-Karasik, Marianna
author_facet Minars, Norman
Blyumin-Karasik, Marianna
author_sort Minars, Norman
collection PubMed
description Background. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy of PDL therapy for mostly facial BCCs. Materials and Methods. Sixteen men and thirteen women (29 total) with 39 biopsy-proven BCCs were treated with 1–4 PDL (595 nm) therapies at 2–4-week intervals. The treatment parameters included pulse energy of 15 J/cm 2, pulse length of 3 millisecond, with no dynamic cooling, and 7 mm spot size. The age of the patients was 30–90 years (mean 73 years). Response rates were evaluated by the clinical assessments with mean followup of 11 months. Results. Twenty-four patients with thirty-two tumors reached at least three months followup: 24/32 (75%) tumors with complete resolution (mean 3 treatment sessions); 5/32 (16%) tumors recurred; 3/32 (9%) tumors with incomplete responses after four treatments. Minimal side effects and discomfort were experienced by the patients with PDL therapy. Conclusion. PDL is a safe, tolerable, and moderately effective method of treating various BCCs. The ideal niche and standardized settings for PDL treatment of BCCs are yet to be determined.
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spelling pubmed-35328782013-01-11 Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series Minars, Norman Blyumin-Karasik, Marianna J Skin Cancer Clinical Study Background. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy of PDL therapy for mostly facial BCCs. Materials and Methods. Sixteen men and thirteen women (29 total) with 39 biopsy-proven BCCs were treated with 1–4 PDL (595 nm) therapies at 2–4-week intervals. The treatment parameters included pulse energy of 15 J/cm 2, pulse length of 3 millisecond, with no dynamic cooling, and 7 mm spot size. The age of the patients was 30–90 years (mean 73 years). Response rates were evaluated by the clinical assessments with mean followup of 11 months. Results. Twenty-four patients with thirty-two tumors reached at least three months followup: 24/32 (75%) tumors with complete resolution (mean 3 treatment sessions); 5/32 (16%) tumors recurred; 3/32 (9%) tumors with incomplete responses after four treatments. Minimal side effects and discomfort were experienced by the patients with PDL therapy. Conclusion. PDL is a safe, tolerable, and moderately effective method of treating various BCCs. The ideal niche and standardized settings for PDL treatment of BCCs are yet to be determined. Hindawi Publishing Corporation 2012 2012-12-13 /pmc/articles/PMC3532878/ /pubmed/23316366 http://dx.doi.org/10.1155/2012/286480 Text en Copyright © 2012 N. Minars and M. Blyumin-Karasik. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Minars, Norman
Blyumin-Karasik, Marianna
Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_full Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_fullStr Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_full_unstemmed Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_short Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_sort treatment of basal cell carcinomas with pulsed dye laser: a case series
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532878/
https://www.ncbi.nlm.nih.gov/pubmed/23316366
http://dx.doi.org/10.1155/2012/286480
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