(1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia

An amino acid, 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, was isolated for the first time from the leaves of Cichorium endivia. The complete assignment of its (1)H and (13)C NMR spectroscopic data was carried out also for the first time based on extensive 1D and 2D NMR experiments. Cytotox...

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Autores principales: Wang, Fu-Xin, Deng, An-Jun, Wei, Jin-Feng, Qin, Hai-Lin, Wang, Ai-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533462/
https://www.ncbi.nlm.nih.gov/pubmed/23304641
http://dx.doi.org/10.1155/2012/254391
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author Wang, Fu-Xin
Deng, An-Jun
Wei, Jin-Feng
Qin, Hai-Lin
Wang, Ai-Ping
author_facet Wang, Fu-Xin
Deng, An-Jun
Wei, Jin-Feng
Qin, Hai-Lin
Wang, Ai-Ping
author_sort Wang, Fu-Xin
collection PubMed
description An amino acid, 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, was isolated for the first time from the leaves of Cichorium endivia. The complete assignment of its (1)H and (13)C NMR spectroscopic data was carried out also for the first time based on extensive 1D and 2D NMR experiments. Cytotoxicity of this isolated compound against HCT-8 and HepG2 human cancer cell lines was evaluated for the first time, with moderate activities being found.
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spelling pubmed-35334622013-01-09 (1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia Wang, Fu-Xin Deng, An-Jun Wei, Jin-Feng Qin, Hai-Lin Wang, Ai-Ping J Anal Methods Chem Research Article An amino acid, 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, was isolated for the first time from the leaves of Cichorium endivia. The complete assignment of its (1)H and (13)C NMR spectroscopic data was carried out also for the first time based on extensive 1D and 2D NMR experiments. Cytotoxicity of this isolated compound against HCT-8 and HepG2 human cancer cell lines was evaluated for the first time, with moderate activities being found. Hindawi Publishing Corporation 2012 2012-12-16 /pmc/articles/PMC3533462/ /pubmed/23304641 http://dx.doi.org/10.1155/2012/254391 Text en Copyright © 2012 Fu-Xin Wang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Fu-Xin
Deng, An-Jun
Wei, Jin-Feng
Qin, Hai-Lin
Wang, Ai-Ping
(1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia
title (1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia
title_full (1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia
title_fullStr (1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia
title_full_unstemmed (1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia
title_short (1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia
title_sort (1)h and (13)c nmr assignments of cytotoxic 3s-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid from the leaves of cichorium endivia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533462/
https://www.ncbi.nlm.nih.gov/pubmed/23304641
http://dx.doi.org/10.1155/2012/254391
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