Absence of the RET+3:T allele in the MTC patients

The mutations of the RET proto-oncogene contributes to the development of MTC by increasing the activity of the receptor encoded by this gene. Variant T of polymorphism rs2435357 located in the enhancer of the RET gene reduces the enhancer’s activity. The opposite effects of rs2435357 and the mutati...

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Detalhes bibliográficos
Principais autores: Borun, Pawel, Jerzy, Sowinski, Ziemnicka, Katarzyna, Kubaszewski, Lukasz, Lipinski, Daniel, Plawski, Andrzej
Formato: Online Atigo Texto
Idioma:English
Publicado em: BioMed Central 2012
Assuntos:
Letter to the Editor
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533580/
https://www.ncbi.nlm.nih.gov/pubmed/23088776
http://dx.doi.org/10.1186/1897-4287-10-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533580/
https://www.ncbi.nlm.nih.gov/pubmed/23088776
http://dx.doi.org/10.1186/1897-4287-10-14

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