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Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis

BACKGROUND: The development of complex responses to hypoxia has played a key role in the evolution of mammals, as inadequate response to this condition is frequently associated with cardiovascular diseases, developmental disorders, and cancers. Though numerous studies have used mice and rats in orde...

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Detalles Bibliográficos
Autores principales: Malik, Assaf, Korol, Abraham, Weber, Mathias, Hankeln, Thomas, Avivi, Aaron, Band, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533650/
https://www.ncbi.nlm.nih.gov/pubmed/23148642
http://dx.doi.org/10.1186/1471-2164-13-615