Cargando…
Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis
BACKGROUND: The development of complex responses to hypoxia has played a key role in the evolution of mammals, as inadequate response to this condition is frequently associated with cardiovascular diseases, developmental disorders, and cancers. Though numerous studies have used mice and rats in orde...
Autores principales: | Malik, Assaf, Korol, Abraham, Weber, Mathias, Hankeln, Thomas, Avivi, Aaron, Band, Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533650/ https://www.ncbi.nlm.nih.gov/pubmed/23148642 http://dx.doi.org/10.1186/1471-2164-13-615 |
Ejemplares similares
-
Hypoxia tolerance, longevity and cancer-resistance in the mole rat Spalax – a liver transcriptomics approach
por: Schmidt, Hanno, et al.
Publicado: (2017) -
Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome
por: Malik, Assaf, et al.
Publicado: (2016) -
Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax
por: Domankevich, Vered, et al.
Publicado: (2016) -
Transcriptome Sequencing of the Blind Subterranean Mole Rat, Spalax galili: Utility and Potential for the Discovery of Novel Evolutionary Patterns
por: Malik, Assaf, et al.
Publicado: (2011) -
Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence
por: Manov, Irena, et al.
Publicado: (2013)