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Anti-Integrin Therapy for Multiple Sclerosis

Integrins are the foremost family of cell adhesion molecules that regulate immune cell trafficking in health and diseases. Integrin alpha4 mediates organ-specific migration of immune cells to the inflamed brain, thereby playing the critical role in the pathogenesis of multiple sclerosis. Anti-alpha4...

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Detalles Bibliográficos
Autores principales: Kawamoto, Eiji, Nakahashi, Susumu, Okamoto, Takayuki, Imai, Hiroshi, Shimaoka, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533681/
https://www.ncbi.nlm.nih.gov/pubmed/23346387
http://dx.doi.org/10.1155/2012/357101