Glycogen Synthase Kinase 3β and Activin/Nodal Inhibition in Human Embryonic Stem Cells Induces a Pre-Neuroepithelial State That Is Required for Specification to a Floor Plate Cell Lineage

The floor plate is one of the major organizers of the developing nervous system through its secretion of sonic hedgehog (Shh). Although the floor plate is located within the neural tube, the derivation of the floor plate during development is still debatable and some studies suggest that floor plate...

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Detalles Bibliográficos
Autores principales: Denham, Mark, Bye, Chris, Leung, Jessie, Conley, Brock J, Thompson, Lachlan H, Dottori, Mirella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533765/
https://www.ncbi.nlm.nih.gov/pubmed/22911885
http://dx.doi.org/10.1002/stem.1204

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