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An efficient RNA interference screening strategy for gene functional analysis
BACKGROUND: RNA interference (RNAi) is commonly applied in genome-scale gene functional screens. However, a one-on-one RNAi analysis that targets each gene is cost-ineffective and laborious. Previous studies have indicated that siRNAs can also affect RNAs that are near-perfectly complementary, and t...
Autores principales: | Chang, Chih-Hung, Wang, Hsiang-Iu, Lu, Hsiang-Chia, Chen, Cheng-En, Chen, Hong-Hwa, Yeh, Hsin-Hung, Tang, Chuan Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533828/ https://www.ncbi.nlm.nih.gov/pubmed/22988976 http://dx.doi.org/10.1186/1471-2164-13-491 |
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