A Japanese case of chronic lymphocytic leukemia with t (1;6)

Chronic lymphocytic leukemia (CLL) rarely exhibits an aggressive clinical course and its patients often have chromosomal deletions or additions. Furthermore, reciprocal translocations are barely observed in CLL. There have only been a few reports of CLL with t(1;6), and here we report the first Asia...

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Detalles Bibliográficos
Autores principales: Harada, Kayo, Ikeda, Kazuhiko, Matsumoto, Hayato, Furukawa, Miki, Takahashi, Hiroshi, Ohkawara, Hiroshi, Noji, Hideyoshi, Tasaki, Kazuhiro, Abe, Masafumi, Ogawa, Kazuei, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533870/
https://www.ncbi.nlm.nih.gov/pubmed/23210523
http://dx.doi.org/10.1186/2162-3619-1-28
Descripción
Sumario:Chronic lymphocytic leukemia (CLL) rarely exhibits an aggressive clinical course and its patients often have chromosomal deletions or additions. Furthermore, reciprocal translocations are barely observed in CLL. There have only been a few reports of CLL with t(1;6), and here we report the first Asian case of CLL with reciprocal translocation t(1;6). Since our case and previously reported CLL patients with t(1;6) consistently showed aggressive clinical course, t(1;6) may define a distinct type of CLL.

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