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Functional region prediction with a set of appropriate homologous sequences-an index for sequence selection by integrating structure and sequence information with spatial statistics

BACKGROUND: The detection of conserved residue clusters on a protein structure is one of the effective strategies for the prediction of functional protein regions. Various methods, such as Evolutionary Trace, have been developed based on this strategy. In such approaches, the conserved residues are...

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Detalles Bibliográficos
Autores principales: Nemoto, Wataru, Toh, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533907/
https://www.ncbi.nlm.nih.gov/pubmed/22643026
http://dx.doi.org/10.1186/1472-6807-12-11