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Feasibility of Azacitidine Added to Standard Chemotherapy in Older Patients with Acute Myeloid Leukemia — A Randomised SAL Pilot Study

INTRODUCTION: Older patients with acute myeloid leukemia (AML) experience short survival despite intensive chemotherapy. Azacitidine has promising activity in patients with low proliferating AML. The aim of this dose-finding part of this trial was to evaluate feasibility and safety of azacitidine co...

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Detalles Bibliográficos
Autores principales: Krug, Utz, Koschmieder, Anja, Schwammbach, Daniela, Gerss, Joachim, Tidow, Nicola, Steffen, Björn, Bug, Gesine, Brandts, Christian H., Schaich, Markus, Röllig, Christoph, Thiede, Christian, Noppeney, Richard, Stelljes, Matthias, Büchner, Thomas, Koschmieder, Steffen, Dührsen, Ulrich, Serve, Hubert, Ehninger, Gerhard, Berdel, Wolfgang E., Müller-Tidow, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534078/
https://www.ncbi.nlm.nih.gov/pubmed/23300745
http://dx.doi.org/10.1371/journal.pone.0052695