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Inhibitory Effect of Tumor Suppressor p53 on Proinflammatory Chemokine Expression in Ovarian Cancer Cells by Reducing Proteasomal Degradation of IκB

Ovarian cancer, one of inflammation-associated cancers, is the fifth leading cause of cancer deaths among women. Inflammation in the tumor microenvironment is associated with peritoneal tumor dissemination and massive ascites, which contribute to high mortality in ovarian cancer. Tumor suppressor p5...

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Detalles Bibliográficos
Autores principales: Son, Deok-Soo, Kabir, Syder M., Dong, Yuan-Lin, Lee, Eunsook, Adunyah, Samuel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534106/
https://www.ncbi.nlm.nih.gov/pubmed/23300534
http://dx.doi.org/10.1371/journal.pone.0051116