Cargando…

Current Concepts on Gastric Carcinoid Tumors

Gastric carcinoid tumors (GCs) are rare lesions representing less than 10% of carcinoid tumors and less than 1% of all stomach neoplasms. There are three distinct types of gastric carcinoids; type I includes the vast majority (70–85%) of these neoplasms that are closely linked to chronic atrophic ga...

Descripción completa

Detalles Bibliográficos
Autores principales: Nikou, George C., Angelopoulos, Theodoros P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534241/
https://www.ncbi.nlm.nih.gov/pubmed/23316222
http://dx.doi.org/10.1155/2012/287825
_version_ 1782475298923610112
author Nikou, George C.
Angelopoulos, Theodoros P.
author_facet Nikou, George C.
Angelopoulos, Theodoros P.
author_sort Nikou, George C.
collection PubMed
description Gastric carcinoid tumors (GCs) are rare lesions representing less than 10% of carcinoid tumors and less than 1% of all stomach neoplasms. There are three distinct types of gastric carcinoids; type I includes the vast majority (70–85%) of these neoplasms that are closely linked to chronic atrophic gastritis. Type II which accounts for 5–10 %, is associated with Zollinger-Ellison syndrome and often occurs in the context of multiple endocrine neoplasia type 1. Type III, finally, represents 15–25% of gastric carcinoids and is characterized by a far more aggressive course. The optimal clinical approach to GCs remains to be elucidated, depending upon type, size, and number of carcinoids. While there is universal agreement about the surgical treatment of type III GCs, current options for type I and II include simple surveillance, endoscopic polypectomy, surgical excision associated with or without surgical antrectomy, or total gastrectomy. Moreover, the introduction of somatostatin analogues could represent another therapeutic option.
format Online
Article
Text
id pubmed-3534241
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-35342412013-01-11 Current Concepts on Gastric Carcinoid Tumors Nikou, George C. Angelopoulos, Theodoros P. Gastroenterol Res Pract Review Article Gastric carcinoid tumors (GCs) are rare lesions representing less than 10% of carcinoid tumors and less than 1% of all stomach neoplasms. There are three distinct types of gastric carcinoids; type I includes the vast majority (70–85%) of these neoplasms that are closely linked to chronic atrophic gastritis. Type II which accounts for 5–10 %, is associated with Zollinger-Ellison syndrome and often occurs in the context of multiple endocrine neoplasia type 1. Type III, finally, represents 15–25% of gastric carcinoids and is characterized by a far more aggressive course. The optimal clinical approach to GCs remains to be elucidated, depending upon type, size, and number of carcinoids. While there is universal agreement about the surgical treatment of type III GCs, current options for type I and II include simple surveillance, endoscopic polypectomy, surgical excision associated with or without surgical antrectomy, or total gastrectomy. Moreover, the introduction of somatostatin analogues could represent another therapeutic option. Hindawi Publishing Corporation 2012 2012-12-17 /pmc/articles/PMC3534241/ /pubmed/23316222 http://dx.doi.org/10.1155/2012/287825 Text en Copyright © 2012 G. C. Nikou and T. P. Angelopoulos. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Nikou, George C.
Angelopoulos, Theodoros P.
Current Concepts on Gastric Carcinoid Tumors
title Current Concepts on Gastric Carcinoid Tumors
title_full Current Concepts on Gastric Carcinoid Tumors
title_fullStr Current Concepts on Gastric Carcinoid Tumors
title_full_unstemmed Current Concepts on Gastric Carcinoid Tumors
title_short Current Concepts on Gastric Carcinoid Tumors
title_sort current concepts on gastric carcinoid tumors
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534241/
https://www.ncbi.nlm.nih.gov/pubmed/23316222
http://dx.doi.org/10.1155/2012/287825
work_keys_str_mv AT nikougeorgec currentconceptsongastriccarcinoidtumors
AT angelopoulostheodorosp currentconceptsongastriccarcinoidtumors