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‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial

BACKGROUND: Most interventions for depression have shown small or no effects. ‘Third wave‘ cognitive therapy and mentalization-based therapy have both gained some ground as treatments of psychological problems. No randomised trial has compared the effects of these two interventions for patients with...

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Autores principales: Jakobsen, Janus Christian, Gluud, Christian, Kongerslev, Mickey, Larsen, Kirsten Aaskov, Sørensen, Per, Winkel, Per, Lange, Theis, Søgaard, Ulf, Simonsen, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534354/
https://www.ncbi.nlm.nih.gov/pubmed/23253305
http://dx.doi.org/10.1186/1471-244X-12-232
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author Jakobsen, Janus Christian
Gluud, Christian
Kongerslev, Mickey
Larsen, Kirsten Aaskov
Sørensen, Per
Winkel, Per
Lange, Theis
Søgaard, Ulf
Simonsen, Erik
author_facet Jakobsen, Janus Christian
Gluud, Christian
Kongerslev, Mickey
Larsen, Kirsten Aaskov
Sørensen, Per
Winkel, Per
Lange, Theis
Søgaard, Ulf
Simonsen, Erik
author_sort Jakobsen, Janus Christian
collection PubMed
description BACKGROUND: Most interventions for depression have shown small or no effects. ‘Third wave‘ cognitive therapy and mentalization-based therapy have both gained some ground as treatments of psychological problems. No randomised trial has compared the effects of these two interventions for patients with major depression. METHODS/ DESIGN: We plan a randomised, parallel group, assessor-blinded superiority clinical trial. During two years we will include 84 consecutive adult participants diagnosed with major depressive disorder. The participants will be randomised to either ‘third wave‘ cognitive therapy versus mentalization-based therapy. The primary outcome will be the Hamilton Rating Scale for Depression at cessation of treatment at 18 weeks. Secondary outcomes will be the proportion of patients with remission, Symptom Checklist 90 Revised, Beck’s Depression Inventory, and The World Health Organisation-Five Well-being Index 1999. DISCUSSION: Interventions for depression have until now shown relatively small effects. Our trial results will provide knowledge about the effects of two modern psychotherapeutic interventions. TRIAL REGISTRATION: ClinicalTrials: NCT01070134
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spelling pubmed-35343542013-01-03 ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial Jakobsen, Janus Christian Gluud, Christian Kongerslev, Mickey Larsen, Kirsten Aaskov Sørensen, Per Winkel, Per Lange, Theis Søgaard, Ulf Simonsen, Erik BMC Psychiatry Study Protocol BACKGROUND: Most interventions for depression have shown small or no effects. ‘Third wave‘ cognitive therapy and mentalization-based therapy have both gained some ground as treatments of psychological problems. No randomised trial has compared the effects of these two interventions for patients with major depression. METHODS/ DESIGN: We plan a randomised, parallel group, assessor-blinded superiority clinical trial. During two years we will include 84 consecutive adult participants diagnosed with major depressive disorder. The participants will be randomised to either ‘third wave‘ cognitive therapy versus mentalization-based therapy. The primary outcome will be the Hamilton Rating Scale for Depression at cessation of treatment at 18 weeks. Secondary outcomes will be the proportion of patients with remission, Symptom Checklist 90 Revised, Beck’s Depression Inventory, and The World Health Organisation-Five Well-being Index 1999. DISCUSSION: Interventions for depression have until now shown relatively small effects. Our trial results will provide knowledge about the effects of two modern psychotherapeutic interventions. TRIAL REGISTRATION: ClinicalTrials: NCT01070134 BioMed Central 2012-12-19 /pmc/articles/PMC3534354/ /pubmed/23253305 http://dx.doi.org/10.1186/1471-244X-12-232 Text en Copyright ©2012 Jakobsen et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Study Protocol
Jakobsen, Janus Christian
Gluud, Christian
Kongerslev, Mickey
Larsen, Kirsten Aaskov
Sørensen, Per
Winkel, Per
Lange, Theis
Søgaard, Ulf
Simonsen, Erik
‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
title ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
title_full ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
title_fullStr ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
title_full_unstemmed ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
title_short ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
title_sort ‘third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. a protocol for a randomised clinical trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534354/
https://www.ncbi.nlm.nih.gov/pubmed/23253305
http://dx.doi.org/10.1186/1471-244X-12-232
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