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‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial
BACKGROUND: Most interventions for depression have shown small or no effects. ‘Third wave‘ cognitive therapy and mentalization-based therapy have both gained some ground as treatments of psychological problems. No randomised trial has compared the effects of these two interventions for patients with...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534354/ https://www.ncbi.nlm.nih.gov/pubmed/23253305 http://dx.doi.org/10.1186/1471-244X-12-232 |
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author | Jakobsen, Janus Christian Gluud, Christian Kongerslev, Mickey Larsen, Kirsten Aaskov Sørensen, Per Winkel, Per Lange, Theis Søgaard, Ulf Simonsen, Erik |
author_facet | Jakobsen, Janus Christian Gluud, Christian Kongerslev, Mickey Larsen, Kirsten Aaskov Sørensen, Per Winkel, Per Lange, Theis Søgaard, Ulf Simonsen, Erik |
author_sort | Jakobsen, Janus Christian |
collection | PubMed |
description | BACKGROUND: Most interventions for depression have shown small or no effects. ‘Third wave‘ cognitive therapy and mentalization-based therapy have both gained some ground as treatments of psychological problems. No randomised trial has compared the effects of these two interventions for patients with major depression. METHODS/ DESIGN: We plan a randomised, parallel group, assessor-blinded superiority clinical trial. During two years we will include 84 consecutive adult participants diagnosed with major depressive disorder. The participants will be randomised to either ‘third wave‘ cognitive therapy versus mentalization-based therapy. The primary outcome will be the Hamilton Rating Scale for Depression at cessation of treatment at 18 weeks. Secondary outcomes will be the proportion of patients with remission, Symptom Checklist 90 Revised, Beck’s Depression Inventory, and The World Health Organisation-Five Well-being Index 1999. DISCUSSION: Interventions for depression have until now shown relatively small effects. Our trial results will provide knowledge about the effects of two modern psychotherapeutic interventions. TRIAL REGISTRATION: ClinicalTrials: NCT01070134 |
format | Online Article Text |
id | pubmed-3534354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35343542013-01-03 ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial Jakobsen, Janus Christian Gluud, Christian Kongerslev, Mickey Larsen, Kirsten Aaskov Sørensen, Per Winkel, Per Lange, Theis Søgaard, Ulf Simonsen, Erik BMC Psychiatry Study Protocol BACKGROUND: Most interventions for depression have shown small or no effects. ‘Third wave‘ cognitive therapy and mentalization-based therapy have both gained some ground as treatments of psychological problems. No randomised trial has compared the effects of these two interventions for patients with major depression. METHODS/ DESIGN: We plan a randomised, parallel group, assessor-blinded superiority clinical trial. During two years we will include 84 consecutive adult participants diagnosed with major depressive disorder. The participants will be randomised to either ‘third wave‘ cognitive therapy versus mentalization-based therapy. The primary outcome will be the Hamilton Rating Scale for Depression at cessation of treatment at 18 weeks. Secondary outcomes will be the proportion of patients with remission, Symptom Checklist 90 Revised, Beck’s Depression Inventory, and The World Health Organisation-Five Well-being Index 1999. DISCUSSION: Interventions for depression have until now shown relatively small effects. Our trial results will provide knowledge about the effects of two modern psychotherapeutic interventions. TRIAL REGISTRATION: ClinicalTrials: NCT01070134 BioMed Central 2012-12-19 /pmc/articles/PMC3534354/ /pubmed/23253305 http://dx.doi.org/10.1186/1471-244X-12-232 Text en Copyright ©2012 Jakobsen et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Study Protocol Jakobsen, Janus Christian Gluud, Christian Kongerslev, Mickey Larsen, Kirsten Aaskov Sørensen, Per Winkel, Per Lange, Theis Søgaard, Ulf Simonsen, Erik ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial |
title | ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial |
title_full | ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial |
title_fullStr | ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial |
title_full_unstemmed | ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial |
title_short | ‘Third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. A protocol for a randomised clinical trial |
title_sort | ‘third wave’ cognitive therapy versus mentalization-based therapy for major depressive disorder. a protocol for a randomised clinical trial |
topic | Study Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534354/ https://www.ncbi.nlm.nih.gov/pubmed/23253305 http://dx.doi.org/10.1186/1471-244X-12-232 |
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