COX5B Regulates MAVS-mediated Antiviral Signaling through Interaction with ATG5 and Repressing ROS Production

Innate antiviral immunity is the first line of the host defense system that rapidly detects invading viruses. Mitochondria function as platforms for innate antiviral signal transduction in mammals through the adaptor protein, MAVS. Excessive activation of MAVS-mediated antiviral signaling leads to d...

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Detalles Bibliográficos
Autores principales: Zhao, Yuanyuan, Sun, Xiaofeng, Nie, Xuanli, Sun, Liwei, Tang, Tie-shan, Chen, Dahua, Sun, Qinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534373/
https://www.ncbi.nlm.nih.gov/pubmed/23308066
http://dx.doi.org/10.1371/journal.ppat.1003086

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