Cargando…
Human Tetherin Exerts Strong Selection Pressure on the HIV-1 Group N Vpu Protein
HIV-1 groups M and N emerged within the last century following two independent cross-species transmissions of SIVcpz from chimpanzees to humans. In contrast to pandemic group M strains, HIV-1 group N viruses are exceedingly rare, with only about a dozen infections identified, all but one in individu...
Autores principales: | Sauter, Daniel, Unterweger, Daniel, Vogl, Michael, Usmani, Shariq M., Heigele, Anke, Kluge, Silvia F., Hermkes, Elisabeth, Moll, Markus, Barker, Edward, Peeters, Martine, Learn, Gerald H., Bibollet-Ruche, Frederic, Fritz, Joëlle V., Fackler, Oliver T., Hahn, Beatrice H., Kirchhoff, Frank |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534379/ https://www.ncbi.nlm.nih.gov/pubmed/23308067 http://dx.doi.org/10.1371/journal.ppat.1003093 |
Ejemplares similares
-
The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function
por: Kluge, Silvia F, et al.
Publicado: (2013) -
Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance
por: Kmiec, Dorota, et al.
Publicado: (2016) -
HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef
por: Sauter, Daniel, et al.
Publicado: (2011) -
β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release
por: Tervo, Hanna-Mari, et al.
Publicado: (2011) -
HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction
por: Schmidt, Sarah, et al.
Publicado: (2011)