Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction

BACKGROUND: Previous studies have noted that drug targets appear to be associated with higher-degree or higher-centrality proteins in interaction networks. These studies explicitly or tacitly make choices of different source databases, data integration strategies, representation of proteins and comp...

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Detalles Bibliográficos
Autores principales: Mora, Antonio, Donaldson, Ian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534413/
https://www.ncbi.nlm.nih.gov/pubmed/23146171
http://dx.doi.org/10.1186/1471-2105-13-294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534413/
https://www.ncbi.nlm.nih.gov/pubmed/23146171
http://dx.doi.org/10.1186/1471-2105-13-294

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