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Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction
BACKGROUND: Previous studies have noted that drug targets appear to be associated with higher-degree or higher-centrality proteins in interaction networks. These studies explicitly or tacitly make choices of different source databases, data integration strategies, representation of proteins and comp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534413/ https://www.ncbi.nlm.nih.gov/pubmed/23146171 http://dx.doi.org/10.1186/1471-2105-13-294 |