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Challenges of the information age: the impact of false discovery on pathway identification

BACKGROUND: Pathways with members that have known relevance to a disease are used to support hypotheses generated from analyses of gene expression and proteomic studies. Using cancer as an example, the pitfalls of searching pathways databases as support for genes and proteins that could represent fa...

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Detalles Bibliográficos
Autores principales: Rog, Colin J, Chekuri, Srinivasa C, Edgerton, Mary E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534555/
https://www.ncbi.nlm.nih.gov/pubmed/23171633
http://dx.doi.org/10.1186/1756-0500-5-647