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Challenges of the information age: the impact of false discovery on pathway identification
BACKGROUND: Pathways with members that have known relevance to a disease are used to support hypotheses generated from analyses of gene expression and proteomic studies. Using cancer as an example, the pitfalls of searching pathways databases as support for genes and proteins that could represent fa...
Autores principales: | Rog, Colin J, Chekuri, Srinivasa C, Edgerton, Mary E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534555/ https://www.ncbi.nlm.nih.gov/pubmed/23171633 http://dx.doi.org/10.1186/1756-0500-5-647 |
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