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Oculus: faster sequence alignment by streaming read compression

BACKGROUND: Despite significant advancement in alignment algorithms, the exponential growth of nucleotide sequencing throughput threatens to outpace bioinformatic analysis. Computation may become the bottleneck of genome analysis if growing alignment costs are not mitigated by further improvement in...

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Detalles Bibliográficos
Autores principales: Veeneman, Brendan A, Iyer, Matthew K, Chinnaiyan, Arul M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534618/
https://www.ncbi.nlm.nih.gov/pubmed/23148484
http://dx.doi.org/10.1186/1471-2105-13-297