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Oculus: faster sequence alignment by streaming read compression
BACKGROUND: Despite significant advancement in alignment algorithms, the exponential growth of nucleotide sequencing throughput threatens to outpace bioinformatic analysis. Computation may become the bottleneck of genome analysis if growing alignment costs are not mitigated by further improvement in...
Autores principales: | Veeneman, Brendan A, Iyer, Matthew K, Chinnaiyan, Arul M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534618/ https://www.ncbi.nlm.nih.gov/pubmed/23148484 http://dx.doi.org/10.1186/1471-2105-13-297 |
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