Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles

BACKGROUND: Pyrroles are widely distributed in nature and important biologically active molecules. The reaction of amines with 2,5-dimethoxytetrahydrofuran is a promising pathway for the synthesis of pharmacologically active pyrroles under microwave irradiation. RESULTS: Microwave-induced polystyren...

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Detalles Bibliográficos
Autores principales: Cárdenas, Rosario Astrid Vargas, Leal, Blanca Olinda Quintanilla, Reddy, Ashwini, Bandyopadhyay, Debasish, Banik, Bimal K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534635/
https://www.ncbi.nlm.nih.gov/pubmed/22726766
http://dx.doi.org/10.1186/2191-2858-2-24
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author Cárdenas, Rosario Astrid Vargas
Leal, Blanca Olinda Quintanilla
Reddy, Ashwini
Bandyopadhyay, Debasish
Banik, Bimal K
author_facet Cárdenas, Rosario Astrid Vargas
Leal, Blanca Olinda Quintanilla
Reddy, Ashwini
Bandyopadhyay, Debasish
Banik, Bimal K
author_sort Cárdenas, Rosario Astrid Vargas
collection PubMed
description BACKGROUND: Pyrroles are widely distributed in nature and important biologically active molecules. The reaction of amines with 2,5-dimethoxytetrahydrofuran is a promising pathway for the synthesis of pharmacologically active pyrroles under microwave irradiation. RESULTS: Microwave-induced polystyrenesulfonate-catalyzed synthesis of pyrroles from amines and 2,5-diemthoxytetrahydrofuran has been accomplished with excellent yield. This method produces pyrroles with polyaromatic amines. CONCLUSION: The present procedure for the synthesis of N-aromatic substituted pyrroles will find useful application in the area of pharmacologically active molecules.
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spelling pubmed-35346352013-01-03 Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles Cárdenas, Rosario Astrid Vargas Leal, Blanca Olinda Quintanilla Reddy, Ashwini Bandyopadhyay, Debasish Banik, Bimal K Org Med Chem Lett Original Article BACKGROUND: Pyrroles are widely distributed in nature and important biologically active molecules. The reaction of amines with 2,5-dimethoxytetrahydrofuran is a promising pathway for the synthesis of pharmacologically active pyrroles under microwave irradiation. RESULTS: Microwave-induced polystyrenesulfonate-catalyzed synthesis of pyrroles from amines and 2,5-diemthoxytetrahydrofuran has been accomplished with excellent yield. This method produces pyrroles with polyaromatic amines. CONCLUSION: The present procedure for the synthesis of N-aromatic substituted pyrroles will find useful application in the area of pharmacologically active molecules. Springer 2012-06-22 /pmc/articles/PMC3534635/ /pubmed/22726766 http://dx.doi.org/10.1186/2191-2858-2-24 Text en Copyright ©2012 Cárdenas et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Cárdenas, Rosario Astrid Vargas
Leal, Blanca Olinda Quintanilla
Reddy, Ashwini
Bandyopadhyay, Debasish
Banik, Bimal K
Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles
title Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles
title_full Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles
title_fullStr Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles
title_full_unstemmed Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles
title_short Microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles
title_sort microwave-assisted polystyrene sulfonate-catalyzed synthesis of novel pyrroles
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534635/
https://www.ncbi.nlm.nih.gov/pubmed/22726766
http://dx.doi.org/10.1186/2191-2858-2-24
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