PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer

The phosphatidylinositol 3′ kinase (PI3K) pathway is commonly activated in breast cancer and aberrations such as PI3K mutations are common. Recent exciting clinical trial results in advanced estrogen receptor-positive (ER) breast cancer support mTOR activation is a major means of estrogen-independen...

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Detalles Bibliográficos
Autores principales: Loi, Sherene, Michiels, Stefan, Baselga, Jose, Bartlett, John M. S., Singhal, Sandeep K., Sabine, Vicky S., Sims, Andrew H., Sahmoud, Tarek, Dixon, J. Michael, Piccart, Martine J., Sotiriou, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534682/
https://www.ncbi.nlm.nih.gov/pubmed/23301057
http://dx.doi.org/10.1371/journal.pone.0053292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534682/
https://www.ncbi.nlm.nih.gov/pubmed/23301057
http://dx.doi.org/10.1371/journal.pone.0053292

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