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Phytol/Phytanic Acid and Insulin Resistance: Potential Role of Phytanic Acid Proven by Docking Simulation and Modulation of Biochemical Alterations

Since activation of PPARγ is the main target for the antidiabetic effect of TZDs, especially when it heterodimerizes with RXR, we aimed to test the potential antidiabetic effect of phytol (250 mg/kg), the natural precursor of phytanic acid, a RXR ligand and/or pioglitazone (5 mg/kg) to diabetic insu...

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Detalles Bibliográficos
Autores principales:	Elmazar, Mohamed M., El-Abhar, Hanan S., Schaalan, Mona F., Farag, Nahla A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534692/ https://www.ncbi.nlm.nih.gov/pubmed/23300941 http://dx.doi.org/10.1371/journal.pone.0045638

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