Exome Capture Sequencing of Adenoma Reveals Genetic Alterations in Multiple Cellular Pathways at the Early Stage of Colorectal Tumorigenesis

Most of colorectal adenocarcinomas are believed to arise from adenomas, which are premalignant lesions. Sequencing the whole exome of the adenoma will help identifying molecular biomarkers that can predict the occurrence of adenocarcinoma more precisely and help understanding the molecular pathways...

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Detalles Bibliográficos
Autores principales: Zhou, Donger, Yang, Liu, Zheng, Liangtao, Ge, Weiting, Li, Dan, Zhang, Yong, Hu, Xueda, Gao, Zhibo, Xu, Jinghong, Huang, Yanqin, Hu, Hanguang, Zhang, Hang, Zhang, Hao, Liu, Mingming, Yang, Huanming, Zheng, Lei, Zheng, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534699/
https://www.ncbi.nlm.nih.gov/pubmed/23301059
http://dx.doi.org/10.1371/journal.pone.0053310

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