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Increased Locomotor Activity and Non-Selective Attention and Impaired Learning Ability in SD Rats after Lentiviral Vector-Mediated RNA Interference of Homer 1a in the Brain
Our previous studies found that Homer 1a, a scaffolding protein localized at the post-synaptic density (PSD) of glutamatergic excitatory synapses, is significantly down-regulated in the brain of spontaneous hypertensive rats (SHR), an animal model of attention deficit hyperactivity disorder (ADHD)....
Autores principales: | Hong, Qin, Yang, Lei, Zhang, Min, Pan, Xiao-Qin, Guo, Mei, Fei, Li, Tong, Mei-Ling, Chen, Rong-Hua, Guo, Xi-Rong, Chi, Xia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534882/ https://www.ncbi.nlm.nih.gov/pubmed/23289010 http://dx.doi.org/10.7150/ijms.4892 |
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