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Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc

Despite the high prevalence of intervertebral disc disease, little is known about changes in intervertebral disc cells and their regenerative potential with ageing and intervertebral disc degeneration. Here we identify populations of progenitor cells that are Tie2 positive (Tie2(+)) and disialogangl...

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Detalles Bibliográficos
Autores principales:	Sakai, Daisuke, Nakamura, Yoshihiko, Nakai, Tomoko, Mishima, Taishi, Kato, Shunichi, Grad, Sibylle, Alini, Mauro, Risbud, Makarand V., Chan, Danny, Cheah, Kathryn S.E., Yamamura, Ken-ichi, Masuda, Koichi, Okano, Hideyuki, Ando, Kiyoshi, Mochida, Joji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535337/ https://www.ncbi.nlm.nih.gov/pubmed/23232394 http://dx.doi.org/10.1038/ncomms2226

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