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Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage
Previous studies have demonstrated that aneuploidy in human embryos is surprisingly frequent with 50–80% of cleavage-stage human embryos carrying an abnormal chromosome number. Here we combine non-invasive time-lapse imaging with karyotypic reconstruction of all blastomeres in four-cell human embryo...
Autores principales: | Chavez, Shawn L., Loewke, Kevin E., Han, Jinnuo, Moussavi, Farshid, Colls, Pere, Munne, Santiago, Behr, Barry, Reijo Pera, Renee A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535341/ https://www.ncbi.nlm.nih.gov/pubmed/23212380 http://dx.doi.org/10.1038/ncomms2249 |
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