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Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex

Impairment of reciprocal social interaction is a core symptom of autism spectrum disorder. Genetic disorders frequently accompany autism spectrum disorder, such as tuberous sclerosis complex caused by haploinsufficiency of the TSC1 and TSC2 genes. Accumulating evidence implicates a relationship betw...

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Detalles Bibliográficos
Autores principales:	Sato, Atsushi, Kasai, Shinya, Kobayashi, Toshiyuki, Takamatsu, Yukio, Hino, Okio, Ikeda, Kazutaka, Mizuguchi, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535343/ https://www.ncbi.nlm.nih.gov/pubmed/23250422 http://dx.doi.org/10.1038/ncomms2295

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