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Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.)

Ergonomic growth phases of annual social insect societies strongly influence horizontally transmitted parasites. Herein, we focused on the impact of temporal changes in host demography on the population structure of a horizontally transmitted parasite. Seasonal fluctuations in prevalence and the occ...

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Autores principales: Popp, Mario, Erler, Silvio, Lattorff, H Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535382/
https://www.ncbi.nlm.nih.gov/pubmed/23233373
http://dx.doi.org/10.1002/mbo3.35
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author Popp, Mario
Erler, Silvio
Lattorff, H Michael G
author_facet Popp, Mario
Erler, Silvio
Lattorff, H Michael G
author_sort Popp, Mario
collection PubMed
description Ergonomic growth phases of annual social insect societies strongly influence horizontally transmitted parasites. Herein, we focused on the impact of temporal changes in host demography on the population structure of a horizontally transmitted parasite. Seasonal fluctuations in prevalence and the occurrence of multiple infections of the gut parasite Crithidia bombi were analyzed in repeatedly sampled populations of two common bumblebee (Bombus spp.) species. Prevalence of C. bombi was greatest in the middle of the foraging season and coincided with the maximal occurrence of multiple infections. Both decline later in the season. The genetic structure of the parasite population also showed strong seasonal fluctuations with a drastic decline in effective population size and an increase in linkage disequilibrium when infection rates were highest. These effects are mainly attributable to significant changes in parasite allele frequencies leading to selection of specific alleles and increasing the frequency of homozygote genotypes in the middle of the season. Within host, competition between parasite genotypes might explain the observed pattern leading to selection of these alleles, and thus a boost of homozygote genotypes in the middle of the season. Toward the end of the season, selection appears to relax and we observed a recovery in linkage equilibrium, as well as an increase in effective population size. This might be explained by genetic exchange in these trypanosomes in natural populations.
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spelling pubmed-35353822013-01-08 Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.) Popp, Mario Erler, Silvio Lattorff, H Michael G Microbiologyopen Original Research Ergonomic growth phases of annual social insect societies strongly influence horizontally transmitted parasites. Herein, we focused on the impact of temporal changes in host demography on the population structure of a horizontally transmitted parasite. Seasonal fluctuations in prevalence and the occurrence of multiple infections of the gut parasite Crithidia bombi were analyzed in repeatedly sampled populations of two common bumblebee (Bombus spp.) species. Prevalence of C. bombi was greatest in the middle of the foraging season and coincided with the maximal occurrence of multiple infections. Both decline later in the season. The genetic structure of the parasite population also showed strong seasonal fluctuations with a drastic decline in effective population size and an increase in linkage disequilibrium when infection rates were highest. These effects are mainly attributable to significant changes in parasite allele frequencies leading to selection of specific alleles and increasing the frequency of homozygote genotypes in the middle of the season. Within host, competition between parasite genotypes might explain the observed pattern leading to selection of these alleles, and thus a boost of homozygote genotypes in the middle of the season. Toward the end of the season, selection appears to relax and we observed a recovery in linkage equilibrium, as well as an increase in effective population size. This might be explained by genetic exchange in these trypanosomes in natural populations. Blackwell Publishing Ltd 2012-12 2012-09-23 /pmc/articles/PMC3535382/ /pubmed/23233373 http://dx.doi.org/10.1002/mbo3.35 Text en © 2012 Published by Blackwell Publishing Ltd. http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
spellingShingle Original Research
Popp, Mario
Erler, Silvio
Lattorff, H Michael G
Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.)
title Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.)
title_full Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.)
title_fullStr Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.)
title_full_unstemmed Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.)
title_short Seasonal variability of prevalence and occurrence of multiple infections shape the population structure of Crithidia bombi, an intestinal parasite of bumblebees (Bombus spp.)
title_sort seasonal variability of prevalence and occurrence of multiple infections shape the population structure of crithidia bombi, an intestinal parasite of bumblebees (bombus spp.)
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535382/
https://www.ncbi.nlm.nih.gov/pubmed/23233373
http://dx.doi.org/10.1002/mbo3.35
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