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Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging

Autophagy is a constitutive lysosomal catabolic pathway that degrades damaged organelles and protein aggregates. Stem cells are characterized by self-renewal, pluripotency, and quiescence; their long life span, limited capacity to dilute cellular waste and spent organelles due to quiescence, along w...

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Detalles Bibliográficos
Autores principales: Phadwal, Kanchan, Watson, Alexander Scarth, Simon, Anna Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535400/
https://www.ncbi.nlm.nih.gov/pubmed/22669258
http://dx.doi.org/10.1007/s00018-012-1032-3