Cargando…

Tuning of Alternative Splicing - Switch From Proto-Oncogene to Tumor Suppressor

STAT5B, a specific member of the STAT family, is intimately associated with prostate tumor progression. While the full form of STAT5B is thought to promote tumor progression, a naturally occurring truncated isoform acts as a tumor suppressor. We previously demonstrated that truncated STAT5 is genera...

Descripción completa

Detalles Bibliográficos
Autores principales: Shchelkunova, Aleksandra, Ermolinsky, Boris, Boyle, Meghan, Mendez, Ivan, Lehker, Michael, Martirosyan, Karen S., Kazansky, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535533/
https://www.ncbi.nlm.nih.gov/pubmed/23289016
http://dx.doi.org/10.7150/ijbs.5194