Analysis of high-throughput RNAi screening data in identifying genes mediating sensitivity to chemotherapeutic drugs: statistical approaches and perspectives

BACKGROUND: High-throughput RNA interference (RNAi) screens have been used to find genes that, when silenced, result in sensitivity to certain chemotherapy drugs. Researchers therefore can further identify drug-sensitive targets and novel drug combinations that sensitize cancer cells to chemotherape...

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Detalles Bibliográficos
Autores principales: Ye, Fei, Bauer, Joshua A, Pietenpol, Jennifer A, Shyr, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535706/
https://www.ncbi.nlm.nih.gov/pubmed/23281588
http://dx.doi.org/10.1186/1471-2164-13-S8-S3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535706/
https://www.ncbi.nlm.nih.gov/pubmed/23281588
http://dx.doi.org/10.1186/1471-2164-13-S8-S3

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