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B-cell selection and the development of autoantibodies

The clearest evidence that B cells play an important role in human autoimmunity is that immunotherapies that deplete B cells are very effective treatments for many autoimmune diseases. All people, healthy or ill, have autoreactive B cells, but not at the same frequency. A number of genes influence t...

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Detalles Bibliográficos
Autores principales: Giltiay, Natalia V, Chappell, Craig P, Clark, Edward A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535718/
https://www.ncbi.nlm.nih.gov/pubmed/23281837
http://dx.doi.org/10.1186/ar3918