Cargando…

The 19 kDa Mycobacterium tuberculosis Lipoprotein (LpqH) Induces Macrophage Apoptosis through Extrinsic and Intrinsic Pathways: A Role for the Mitochondrial Apoptosis-Inducing Factor

We describe the association of caspase-dependent and caspase-independent mechanisms in macrophage apoptosis induced by LpqH, a 19 kDa Mycobacterium tuberculosis lipoprotein. LpqH triggered TLR2 activation, with upregulation of death receptors and ligands, which was followed by a death receptor signa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sánchez, Alejandro, Espinosa, Patricia, García, Teresa, Mancilla, Raúl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536062/ https://www.ncbi.nlm.nih.gov/pubmed/23316255 http://dx.doi.org/10.1155/2012/950503

Ejemplares similares

Effect and Mechanism of Mycobacterium tuberculosis Lipoprotein LpqH in NLRP3 Inflammasome Activation in Mouse Ana-1 Macrophage
por: Liu, Liting, et al.
Publicado: (2021)

Mycobacterium tuberculosis extracellular vesicle-associated lipoprotein LpqH as a potential biomarker to distinguish paratuberculosis infection or vaccination from tuberculosis infection
por: Palacios, Ainhoa, et al.
Publicado: (2019)

An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis
por: Krishnananthasivam, Shivankari, et al.
Publicado: (2023)

Author Correction: An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis
por: Krishnananthasivam, Shivankari, et al.
Publicado: (2023)

Immunoreactivity of the Mycobacterium avium subsp. paratuberculosis 19-kDa lipoprotein
por: Huntley, Jason FJ, et al.
Publicado: (2005)

67-kDa laminin receptor and cGMP induced cancer-selective apoptosis
por: Kumazoe, Motofumi, et al.
Publicado: (2013)

Hexavalent chromium intoxication induces intrinsic and extrinsic apoptosis in human renal cells
por: Wu, Yen-Hung, et al.
Publicado: (2020)

Activation of the intrinsic and extrinsic pathways in high pressure-induced apoptosis of murine erythroleukemia cells
por: Yamaguchi, Takeo, et al.
Publicado: (2007)

Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages
por: Chen, Jing, et al.
Publicado: (2021)

Extrinsic or Intrinsic Apoptosis by Curcumin and Light: Still a Mystery
por: Laubach, Vesselina, et al.
Publicado: (2019)

16 kDa vasoinhibin binds to integrin alpha5 beta1 on endothelial cells to induce apoptosis
por: Morohoshi, Kazunori, et al.
Publicado: (2018)

Involvement of Both Extrinsic and Intrinsic Apoptotic Pathways in Tridecylpyrrolidine-Diol Derivative-Induced Apoptosis In Vitro
por: Nosalova, Natalia, et al.
Publicado: (2023)

Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC
por: Liang, Jingxi, et al.
Publicado: (2023)

Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis
por: Wilkinson, Katalin A, et al.
Publicado: (2009)

Translocator protein 18 kDa regulates retinal neuron apoptosis and pyroptosis in glaucoma
por: Zeng, Zhou, et al.
Publicado: (2023)

Potential involvement of the 18 kDa translocator protein and reactive oxygen species in apoptosis of THP-1 macrophages induced by sonodynamic therapy
por: Sun, Xin, et al.
Publicado: (2018)

Iridovirus CARD Protein Inhibits Apoptosis through Intrinsic and Extrinsic Pathways
por: Chen, Chien-Wen, et al.
Publicado: (2015)

Intrinsic and extrinsic apoptosis responses in leukaemia cells following daunorubicin treatment
por: Al-Aamri, Hussain Mubarak, et al.
Publicado: (2021)

Orf Virus Encoded Protein ORFV119 Induces Cell Apoptosis Through the Extrinsic and Intrinsic Pathways
por: Li, Wei, et al.
Publicado: (2018)

Coptisine Induces Apoptosis in Human Hepatoma Cells Through Activating 67-kDa Laminin Receptor/cGMP Signaling
por: Zhou, Li, et al.
Publicado: (2018)

The 89-kDa PARP1 cleavage fragment serves as a cytoplasmic PAR carrier to induce AIF-mediated apoptosis
por: Mashimo, Masato, et al.
Publicado: (2020)

33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways
por: Guo, Chunmei, et al.
Publicado: (2020)

Pregnenolone, a cholesterol metabolite, induces glioma cell apoptosis via activating extrinsic and intrinsic apoptotic pathways
por: XIAO, XIAO, et al.
Publicado: (2014)

Satureja khuzistanica Jamzad essential oil prevents doxorubicin-induced apoptosis via extrinsic and intrinsic mitochondrial pathways
por: Seyedan, Ali Al, et al.
Publicado: (2020)

Magnolol Induces the Extrinsic/Intrinsic Apoptosis Pathways and Inhibits STAT3 Signaling-Mediated Invasion of Glioblastoma Cells
por: Yueh, Po-Fu, et al.
Publicado: (2021)

Inter-organellar communication with mitochondria regulates both the intrinsic and extrinsic pathways of apoptosis
por: Renault, Thibaud T., et al.
Publicado: (2013)

The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis
por: Soares, Fraser, et al.
Publicado: (2014)

Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling
por: Wachter, Franziska, et al.
Publicado: (2013)

Crystal Structure of Bombyx mori Lipoprotein 6: Comparative Structural Analysis of the 30-kDa Lipoprotein Family
por: Pietrzyk, Agnieszka J., et al.
Publicado: (2014)

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation
por: Ouali, Boimpoundi Eunice Flavie, et al.
Publicado: (2020)

The hydrolase LpqI primes mycobacterial peptidoglycan recycling
por: Moynihan, Patrick J., et al.
Publicado: (2019)

The 30-kDa and 38-kDa antigens from Mycobacterium tuberculosis induce partial maturation of human dendritic cells shifting CD4(+) T cell responses towards IL-4 production
por: Heuer, Marion, et al.
Publicado: (2013)

Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway
por: Yaoxian, Wang, et al.
Publicado: (2013)

GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway
por: Mahata, Barun, et al.
Publicado: (2015)

Blockage of both the extrinsic and intrinsic pathways of diazinon-induced apoptosis in PaTu cells by magnesium oxide and selenium nanoparticles
por: Shiri, Mahdi, et al.
Publicado: (2016)

Natural Gallic Acid and Methyl Gallate Induces Apoptosis in Hela Cells through Regulation of Intrinsic and Extrinsic Protein Expression
por: Abdullah, Hasmah, et al.
Publicado: (2023)

Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma
por: Hamsa, Thayele Purayil, et al.
Publicado: (2011)

Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis
por: Goc, Anna, et al.
Publicado: (2012)

RMP/URI inhibits both intrinsic and extrinsic apoptosis through different signaling pathways
por: Ji, Yuan, et al.
Publicado: (2019)

siRNA-mediated silencing of the 37/67-kDa high affinity laminin receptor in Hep3B cells induces apoptosis
por: Susantad, Tharinee, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_otvi73b1g0rua0b87k5innqrhj