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Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity
BACKGROUND: The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53 activation is regulated by post-translational modification, including phosphorylation of the N-terminal transact...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35361/ https://www.ncbi.nlm.nih.gov/pubmed/11483158 http://dx.doi.org/10.1186/1471-2121-2-12 |