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Deterministic global optimization algorithm based on outer approximation for the parameter estimation of nonlinear dynamic biological systems

BACKGROUND: The estimation of parameter values for mathematical models of biological systems is an optimization problem that is particularly challenging due to the nonlinearities involved. One major difficulty is the existence of multiple minima in which standard optimization methods may fall during...

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Detalles Bibliográficos
Autores principales:	Miró, Anton, Pozo, Carlos, Guillén-Gosálbez, Gonzalo, Egea, Jose A, Jiménez, Laureano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536584/ https://www.ncbi.nlm.nih.gov/pubmed/22574924 http://dx.doi.org/10.1186/1471-2105-13-90

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