Cargando…

Inferring biochemical reaction pathways: the case of the gemcitabine pharmacokinetics

BACKGROUND: The representation of a biochemical system as a network is the precursor of any mathematical model of the processes driving the dynamics of that system. Pharmacokinetics uses mathematical models to describe the interactions between drug, and drug metabolites and targets and through the s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lecca, Paola, Morpurgo, Daniele, Fantaccini, Gianluca, Casagrande, Alessandro, Priami, Corrado
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536593/ https://www.ncbi.nlm.nih.gov/pubmed/22640931 http://dx.doi.org/10.1186/1752-0509-6-51

Ejemplares similares

Algorithmic Modeling Quantifies the Complementary Contribution of Metabolic Inhibitions to Gemcitabine Efficacy
por: Kahramanoğullari, Ozan, et al.
Publicado: (2012)

Modelling non-homogeneous stochastic reaction-diffusion systems: the case study of gemcitabine-treated non-small cell lung cancer growth
por: Lecca, Paola, et al.
Publicado: (2012)

Bayesian inference of biochemical kinetic parameters using the linear noise approximation
por: Komorowski, Michał, et al.
Publicado: (2009)

Integrating Bayesian variable selection with Modular Response Analysis to infer biochemical network topology
por: Santra, Tapesh, et al.
Publicado: (2013)

A model reduction method for biochemical reaction networks
por: Rao, Shodhan, et al.
Publicado: (2014)

Inferring Biochemical Reactions and Metabolite Structures to Understand Metabolic Pathway Drift
por: Belcour, Arnaud, et al.
Publicado: (2020)

A method for inverse bifurcation of biochemical switches: inferring parameters from dose response curves
por: Otero-Muras, Irene, et al.
Publicado: (2014)

Study of Meta-analysis strategies for network inference using information-theoretic approaches
por: Pham, Ngoc C., et al.
Publicado: (2017)

A Novel Multi-Scale Modeling Approach to Infer Whole Genome Divergence
por: Reuveni, Eli, et al.
Publicado: (2012)

A new dynamical layout algorithm for complex biochemical reaction networks
por: Wegner, Katja, et al.
Publicado: (2005)

Inferring branching pathways in genome-scale metabolic networks
por: Pitkänen, Esa, et al.
Publicado: (2009)

IPCO: Inference of Pathways from Co-variance analysis
por: Das, Mrinmoy, et al.
Publicado: (2020)

Set-base dynamical parameter estimation and model invalidation for biochemical reaction networks
por: Rumschinski, Philipp, et al.
Publicado: (2010)

Parametric sensitivity analysis for biochemical reaction networks based on pathwise information theory
por: Pantazis, Yannis, et al.
Publicado: (2013)

A Dominated Coupling From The Past algorithm for the stochastic simulation of networks of biochemical reactions
por: Hemberg, Martin, et al.
Publicado: (2008)

Data-driven inference for the spatial scan statistic
por: Almeida, Alexandre CL, et al.
Publicado: (2011)

Machine Learning for Causal Inference in Biological Networks: Perspectives of This Challenge
por: Lecca, Paola
Publicado: (2021)

Corrigendum: Machine Learning for Causal Inference in Biological Networks: Perspectives of This Challenge
por: Lecca, Paola
Publicado: (2022)

Insight into Biochemical Characterization of Plant Sesquiterpene Synthases
por: Manczak, Tom, et al.
Publicado: (2016)

Inferring Stable Acquisition Durations for Applications of Perfusion Imaging in Oncology
por: Hobbs, Brian P, et al.
Publicado: (2015)

Dynamic interaction network inference from longitudinal microbiome data
por: Lugo-Martinez, Jose, et al.
Publicado: (2019)

An unsupervised classification method for inferring original case locations from low-resolution disease maps
por: Brownstein, John S, et al.
Publicado: (2006)

TIGRESS: Trustful Inference of Gene REgulation using Stability Selection
por: Haury, Anne-Claire, et al.
Publicado: (2012)

Simplification of biochemical models: a general approach based on the analysis of the impact of individual species and reactions on the systems dynamics
por: Surovtsova, Irina, et al.
Publicado: (2012)

Functional networks inference from rule-based machine learning models
por: Lazzarini, Nicola, et al.
Publicado: (2016)

Coincidence analysis: a new method for causal inference in implementation science
por: Whitaker, Rebecca Garr, et al.
Publicado: (2020)

Using Bayesian inference to estimate plausible muscle forces in musculoskeletal models
por: Johnson, Russell T., et al.
Publicado: (2022)

A framework for integrating inferred movement behavior into disease risk models
por: Dougherty, Eric R., et al.
Publicado: (2022)

Inferring the impact of humanitarian responses on population mortality: methodological problems and proposals
por: Checchi, Francesco
Publicado: (2023)

Towards optimal design of anti-malarial pharmacokinetic studies
por: Simpson, Julie A, et al.
Publicado: (2009)

Pharmacokinetics and pharmacodynamics of natalizumab in pediatric patients with RRMS
por: Ghezzi, Angelo, et al.
Publicado: (2019)

Elucidation of functional consequences of signalling pathway interactions
por: Ihekwaba, Adaoha EC, et al.
Publicado: (2009)

An information-oriented paradigm in evaluating accuracy and agreement in radiology
por: Casagrande, Alberto, et al.
Publicado: (2023)

Differences in the INR evaluation of two different thromboplastins in patients with positivity to lupus anticoagulant in ongoing oral anticoagulation
por: Ferrazzi, Paola, et al.
Publicado: (2010)

Common biochemical properties of metabolic genes recurrently dysregulated in tumors
por: Oruganty, Krishnadev, et al.
Publicado: (2020)

Multiplex genotyping system for efficient inference of matrilineal genetic ancestry with continental resolution
por: van Oven, Mannis, et al.
Publicado: (2011)

Accurate inference of shoot biomass from high-throughput images of cereal plants
por: Golzarian, Mahmood R, et al.
Publicado: (2011)

Inferring Active and Prognostic Ligand-Receptor Pairs with Interactions in Survival Regression Models
por: Ruggeri, Christina, et al.
Publicado: (2015)

hmmIBD: software to infer pairwise identity by descent between haploid genotypes
por: Schaffner, Stephen F., et al.
Publicado: (2018)

MSCFS: inferring circRNA functional similarity based on multiple data sources
por: Shu, Liang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pam812rlrt1rn9gpqn90e45815