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Activated protein C ameliorates Bacillus anthracis lethal toxin-induced lethal pathogenesis in rats

BACKGROUND: Lethal toxin (LT) is a major virulence factor of Bacillus anthracis. Sprague Dawley rats manifest pronounced lung edema and shock after LT treatments, resulting in high mortality. The heart failure that is induced by LT has been suggested to be a principal mechanism of lung edema and mor...

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Detalles Bibliográficos
Autores principales:	Kau, Jyh-Hwa, Shih, Yung-Luen, Lien, Te-Sheng, Lee, Chin-Cheng, Huang, Hsin-Hsien, Lin, Hung-Chi, Sun, Der-Shan, Chang, Hsin-Hou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536616/ https://www.ncbi.nlm.nih.gov/pubmed/23170801 http://dx.doi.org/10.1186/1423-0127-19-98

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