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The Underlying Molecular and Network Level Mechanisms in the Evolution of Robustness in Gene Regulatory Networks

Gene regulatory networks show robustness to perturbations. Previous works identified robustness as an emergent property of gene network evolution but the underlying molecular mechanisms are poorly understood. We used a multi-tier modeling approach that integrates molecular sequence and structure inf...

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Detalles Bibliográficos
Autores principales:	Pujato, Mario, MacCarthy, Thomas, Fiser, Andras, Bergman, Aviv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536627/ https://www.ncbi.nlm.nih.gov/pubmed/23300434 http://dx.doi.org/10.1371/journal.pcbi.1002865

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